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Effects of Microgravity on Insulin Production – GSMST SpaceLab Entry

October 9, 2019


Hi, I’m Brian. I’m 16. Hi. I’m Adidia. I’m also 16. Hi, I’m Shawn. I’m 17. Diabetes is a condition where a person is
unable to control their blood sugar levels… …to deficient or insufficient insulin. This condition affects
almost 346 million people globally. People with diabetes need insulin shots
to control their blood sugar levels. Insulin is a protein produced
in the pancreas. In the past,
we’ve been getting our insulin… …from cows and pigs
to treat human diabetes. But these days, we produce insulin
with the help of bacteria and yeast… …through genetic recombination. With recombinant DNA… …we’re able to take the DNA
of one organism… …and insert it into the DNA of another. Our goal with this experiment… …is to see how microgravity
and other factors in space… …affect insulin production in bacteria. Studies have already shown that bacteria
grow larger and reproduce faster… …than bacteria on Earth. We believe that this extends
to protein production… …and that the bacteria will produce
more insulin than they would on Earth. For our experiment, we’ll take
one set of bacteria aboard Habitat II… …and keep another set of bacteria
in a culture on Earth. Then we’ll compare
the two groups of bacteria… …and compare rates
of insulin production. Hopefully this will allow for more
efficient insulin production in the future. Vote for us.

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12 Comments

  • Reply Asad Pervez December 16, 2011 at 5:18 pm

    u guyz from UK??

  • Reply Brian Barr December 18, 2011 at 1:30 pm

    @TheSouthAlpha Haha no, we're from the US. : )

  • Reply D4GG312 December 21, 2011 at 12:11 pm

    good job guys-

  • Reply Kevin Edwards December 22, 2011 at 4:30 pm

    Good jobs guys, and interesting idea.

  • Reply Ayush Agarwal December 24, 2011 at 5:46 am

    Hey guys, interesting idea. 🙂 Check out ours in ours in my channel.

  • Reply Shawn Albert January 19, 2012 at 12:05 am

    Awesome video! Rooting for you guys. 🙂

  • Reply Vibhor Khanna January 19, 2012 at 1:52 am

    GSMST! 🙂

  • Reply omnicomment January 19, 2012 at 5:28 pm

    Hey guys – just my two cents – have you thought about maybe extending the scope of the experiment to check the production of insulin by the human pancreatic cells themselves? You could have cultures obtained from a single person sent to the ISS, and another maintained in the lab – checking the production of the hormone. It would help the astronauts and their nutritionists massively by customizing diets to any changes in natural insulin levels brought about by microgravity habitation.

  • Reply Brian Barr January 19, 2012 at 10:24 pm

    @omnicomment That is actually a great idea! If our experiment gets chosen -fingers crossed- then we will definitely look into the possibility of increasing the scope of the project. Thanks for your contribution. : )

  • Reply Mituhori January 21, 2012 at 11:51 pm

    I like the shirt.

  • Reply Casal Trapo January 22, 2012 at 12:59 am

    nice one

  • Reply MizukiSakai January 22, 2012 at 6:54 pm

    go gsmst 🙂 great idea!

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